Resident Evil has taken a huge bite out of the weekend box office. Zach Cregger’s new take on the video-game horror franchise opened at No. 1 with $60 million from 3,684 locations, giving the fall movie season an immediate new leader.
Last weekend’s champion, Practical Magic 2, held onto second place with $12.155 million and has now topped $50 million in two weekends. Spider-Man: Brand New Day remained a major draw in its seventh weekend, while Christopher Nolan’s The Odyssey and the long-awaited Coyote vs. Acme completed a Top 5 filled with very different kinds of big-screen entertainment.
1. Resident Evil — $60 Million
Resident Evil arrived with the kind of opening that immediately changes the conversation around the weekend. The Sony release earned $60 million in its first three days, for a $16,287 per-theater average across 3,684 locations.
Rather than simply revisiting the previous film series, writer-director Zach Cregger builds this version as a nerve-jangling horror story set inside the franchise’s familiar nightmare world. Austin Abrams leads the film as Bryan, a medical courier whose bad night becomes much worse once he is pulled toward Raccoon City. Read our Resident Evil review for more on why this new chapter works best when it leans into dread, chaos and the franchise’s creature-feature instincts.
2. Practical Magic 2 — $12.155 Million
Practical Magic 2 slipped to second place in its sophomore frame, but its $12.155 million weekend brings its domestic total to $50.032 million. The Warner Bros. sequel remained in 4,163 locations, a sign that audiences are still making room for the Owens sisters even after Resident Evil’s very large debut.
Sandra Bullock and Nicole Kidman return as Sally and Gillian Owens in the long-awaited follow-up, directed by Susanne Bier. The film opened with $30 million last weekend, ending Spider-Man: Brand New Day’s six-week run at No. 1; catch up on that milestone in our previous weekend box office report. For our full take on the sequel itself, read the Practical Magic 2 review.
3. Spider-Man: Brand New Day — $6.5 Million
Spider-Man: Brand New Day continued its remarkably durable run with $6.5 million in weekend seven. The Sony superhero release has now reached $944.502 million domestically, an enormous total that keeps Tom Holland’s latest Peter Parker adventure firmly in the box-office conversation even as fresh competition arrives.
Playing in 3,018 locations, the film averaged $2,154 per theater this weekend. Directed by Destin Daniel Cretton, Brand New Day follows a Spider-Man still dealing with the consequences of No Way Home while trying to find his footing again. Read our Spider-Man: Brand New Day review for a closer look at the film’s more grounded next step for Peter.
4. The Odyssey — $4.9 Million
Christopher Nolan’s The Odyssey held fourth place with $4.9 million from 1,546 locations. Its $3,169 per-theater average and $609.758 million domestic total underline how much staying power the epic has found with moviegoers.
Matt Damon leads the sprawling adaptation as Odysseus, with Nolan bringing the scale and intensity audiences expect from one of his event films. The movie has kept drawing viewers long after its opening rush, and it remains a notable counterpoint to the more franchise-driven titles surrounding it in this week’s Top 5. Read our The Odyssey review for our full reaction to Nolan’s ambitious voyage.
5. Coyote vs. Acme — $4.512 Million
Coyote vs. Acme rounded out the Top 5 with $4.512 million from 3,034 locations, lifting its domestic total to $54.816 million. The live-action/animation hybrid has continued to find an audience after a release journey that made it one of the more unusual movie stories of the year.
Directed by Dave Green and starring Will Forte, John Cena and Lana Condor, the film gives Wile E. Coyote an unexpected day in court against the company whose products have failed him for generations. It is a premise that sounds wild on paper, but the movie’s heart and affection for its Looney Tunes icon are exactly what make it land. Read our Coyote vs. Acme review for more.
Resident Evil Gives the Fall Box Office a New Leader
With a $60 million opening, Resident Evil did more than claim the top spot: it gave theaters a clear new event movie heading into the next stretch of the fall season. It also pushed a varied group of holdovers into a crowded but healthy-looking Top 5, from supernatural romance and superhero spectacle to a prestige epic and Looney Tunes legal comedy.
There is plenty to dig into beyond the numbers this week. Every title in the Top 5 has a Seat42F review, so use the links above to find out which ones deserve a spot on your next moviegoing list.
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| Weekend | Locations | Average | Total | ||
|---|---|---|---|---|---|
| 1 | Resident Evil | $60,000,000 | 3,684 | 16,287 | $60,000,000 |
| 2 | Practical Magic 2 | $12,155,000 | 4,163 | 2,920 | $50,032,000 |
| 3 | Spider-Man: Brand New Day | $6,500,000 | 3,018 | 2,154 | 944,502,000 |
| 4 | Odyssey, The | $4,900,000 | 1,546 | $3,169 | 609,758,000 |
| 5 | Coyote vs. Acme | $4,512,135 | 3,034 | 1,487 | $54,816,201 |
| 6 | Runner | $3,180,074 | 2,473 | 1,286 | 11,986,902 |
| 7 | Daniel and the Fiery Furnace | $3,140,000 | 1,525 | 2,059 | 3,140,000 |
| 8 | Transformers: The Movie 40th Anniversary, The | $3,103,922 | 1,454 | 2,135 | 4,156,531 |
| 9 | Weight, The | $2,315,162 | 1,504 | $1,539 | 2,315,162 |
| 10 | Buddy | $1,929,101 | 1,532 | 1,259 | 24,833,065 |
| 11 | Shaun the Sheep: The Beast of Mossy Bottom | $1,904,000 | 2,183 | $872 | 1,904,000 |
| 12 | Insidious: Out of the Further | $1,850,000 | 1,740 | 1,063 | 63,755,000 |
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Thomas Miller is the founder and Editor-in-Chief of Seat42F, covering television, movies and streaming entertainment. He launched Seat42F in 2007 and has spent nearly two decades covering the entertainment industry.


